Samples

Agent

MIC/MBC (μg/mL)

FIC/FBC

FICI/FBCI²

Outcome

Alone

Combination¹

MSSA ATCC 25923³

Acacetin

5/20

1.25/5

0.25/0.25

0.5/0.5

Synergistic/Synergistic

Ampicillin

8/16

2/4

0.25/0.25

MRSA ATCC 33591⁴

Acacetin

20/40

5/10

0.25/0.25

0.5/0.5

Synergistic/Synergistic

Ampicillin

1024/2048

256/512

0.25/0.25

MRSA 1⁵

Acacetin

10/40

2.5/10

0.25/0.25

0.5/0.5

Synergistic/Synergistic

Ampicillin

1024/2048

256/512

0.25/0.25

MRSA 2

Acacetin

20/80

5/20

0.25/0.25

0.5/0.5

Synergistic/Synergistic

Ampicillin

128/256

32/64

0.25/0.25

MRSA 3

Acacetin

40/80

10/20

0.25/0.25

0.5/0.5

Synergistic/Synergistic

Ampicillin

1024/2048

256/512

0.25/0.25

MRSA 4

Acacetin

20/80

5/10

0.25/0.125

0.5/0.375

Synergistic/Synergistic

Ampicillin

256/512

64/128

0.25/0.25

MRSA 5

Acacetin

40/160

10/40

0.25/0.25

0.5/0.5

Synergistic/Synergistic

Ampicillin

128/256

32/64

0.25/0.25

MRSA 6

Acacetin

80/160

20/40

0.25/0.25

0.5/0.75

Synergistic/Additive

Ampicillin

256/256

64/128

0.25/0.5

MRSA 7

Acacetin

20/40

5/10

0.25/0.25

0.75/0.5

Additive/Synergistic

Ampicillin

128/512

64/128

0.5/0.25

MRSA 8

Acacetin

10/20

2.5/10

0.25/0.5

0.5/0.75

Synergistic/Additive

Ampicillin

128/256

32/64

0.25/0.25

MRSA 9

Acacetin

10/40

2.5/10

0.25/0.25

0.5/0.375

Synergistic/Synergistic

Ampicillin

128/512

32/64

0.25/0.125

MRSA 10

Acacetin

40/80

10/20

0.25/0.25

0.75/0.75

Additive/Additive

Ampicillin

64/128

32/64

0.5/0.5

MRSA 11

Acacetin

20/80

5/10

0.25/0.125

0.75/0.625

Additive/Additive

Ampicillin

128/256

64/128

0.5/0.5

MRSA 12

Acacetin

80/160

20/40

0.25/0.25

0.5/0.75

Synergistic/Additive

Ampicillin

256/256

64/128

0.25/0.5

MRSA 13

Acacetin

80/160

20/40

0.25/0.25

0.5/0.75

Synergistic/Additive

Ampicillin

64/128

16/64

0.25/0.5

MRSA 14

Acacetin

40/80

10/20

0.25/0.25

0.5/0.5

Synergistic/Synergistic

Ampicillin

128/256

32/64

0.25/0.25

MRSA 15

Acacetin

40/160

10/40

0.25/0.25

0.5/0.75

Synergistic/Additive

Ampicillin

64/128

16/64

0.25/0.5

MRSA 16

Acacetin

80/160

20/40

0.25/0.25

0.75/0.5

Additive/Synergistic

Ampicillin

128/256

64/64

0.5/0.25

MRSA 17

Acacetin

10/20

2.5/5

0.25/0.25

0.5/0.5

Synergistic/Synergistic

Ampicillin

128/256

32/64

0.25/0.25

MRSA 18

Acacetin

80/160

20/40

0.25/0.25

0.5/0.5

Synergistic/Synergistic

Ampicillin

64/128

16/32

0.25/0.25

MRSA 19

Acacetin

80/160

20/40

0.25/0.25

0.75/0.75

Additive/Additive

Ampicillin

64/128

32/64

0.5/0.5

MRSA 20

Acacetin

40/80

10/20

0.25/0.25

0.5/0.375

Synergistic/Synergistic

Ampicillin

128/512

32/64

0.25/0.125